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Search Results for " histamine n-methyltransferase "

Targets Recommended: Histone Methyltransferase Antifolate Histamine Receptor

5

抑制剂 & 化合物

1

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T8548	Metoprine	Histone Methyltransferase; Antifolate; Histamine Receptor	Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Metoprine 是一种有效的组胺 N-甲基转移酶抑制剂，具有抗肿瘤活性。它是一种二氨基嘧啶衍生物，可以透过血脑屏障，并通过抑制 HMT 增加脑组胺水平。
T68694	Quinacrine acetate
	Quinacrine acetate is a histamine N-methyltransferase inhibitor.
T23367	SKF 91488 dihydrochloride	Others	Others
	histamine N-methyltransferase inhibitor
T22242	Amodiaquine hydrochloride
	Amodiaquine dihydrochloride (Amodiaquin dihydrochloride) 是一种4-氨基喹啉类抗疟剂，是一种有效的口服活性的组胺 N-甲基转移酶 (histamine N-methyltransferase) 抑制剂，Ki 值为 18.6 nM。Amodiaquine dihydrochloride 也是一种Nurr1激动剂，可特异性结合Nurr1的配体结合域，EC50约为20 μM，具有抗炎作用。
TMIH-0028	2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl 1-Methylhistamine-d3 Dihydrochloride
	2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl 是 2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的氘代化合物。2-(1-(methyl)-1H-imidazol-4-yl)ethan-1-amine 2HCl 的 CAS 号为 6481-48-7。1-Methylhistamine dihydrochloride 是组胺代谢物。

化合物

Cat.No: T8548

Target: Histone Methyltransferase, Antifolate, Histamine Receptor

Quinacrine acetate

Cat.No: T68694

SKF 91488 dihydrochloride

Cat.No: T23367

Target: Others

Amodiaquine hydrochloride

Cat.No: T22242

2-(1-(methyl-d3)-1H-imidazol-4-yl)ethan-1-amine 2HCl

Cat.No: TMIH-0028

Synonym: 1-Methylhistamine-d3 Dihydrochloride

Cat. No.	Product Name	Target	Signaling Pathways
T8790	1-Methylhistamine dihydrochloride	Endogenous Metabolite	Metabolism
	1-Methylhistamine dihydrochloride 是组胺代谢物。

天然产物

1-Methylhistamine dihydrochloride

Cat.No: T8790

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02340	HNMT Protein, Human, Recombinant (GST) HMT,HNMT-S1,HNMT-S2,histamine...	Human	E. coli
	HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabolism of histamine in the rat brain, is potently inhibited by 9-amino-1,2,3,4-tetrahydroacridine (tacrine). Methylation is an important pathway in the biotransformation of many drugs, neurotransmitters, and xenobiotic compounds. Histamine N-methyltransferase (HNMT) catalyzes the N ...

重组蛋白

HNMT Protein, Human, Recombinant (GST)

Cat.No: TMPY-02340

Species: Human

Expression System: E. coli

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